Pleurodonte isabella is endemic to Barbados, an island of the Lesser Antilles in the Caribbean. Although endemic, this species has no problems with increasing development and human influence. It is found both in wooded areas and in gardens in the suburbs of cities.
They are not difficult animals but do like a higher humidity. In terms of nutrition, they prefer to eat cucumber, carrots, sweet potato and fish flakes.
The approximately 12 eggs are neatly buried under the ground where they hatch after about 10 days. The animals themselves grow to a maximum of 2.5 cm.